webinar

Importance of serology testing in COVID-19 vaccinations

To confirm COVID-19 vaccine efficacy, some countries in ASEAN are carrying out serology testing. But is it necessary? Dr Leong Hoe Nam and Asst Prof Mondej Sookpranee, infectious disease experts, share their views.

Speaker:
Dr Leong Hoe Nam
Infectious Diseases Physician, Rophi Clinic

Asst Prof Mondej Sookpranee
Infectious disease specialist, Medpark Hospital Thailand

Summary

There are several types of responses in vaccinated individuals: no response, a rapid decline in antibody levels or a slow decline over time, or persistent levels of antibodies over a long time. This means that 1/3 or half of vaccinated individuals are at risk because of the decline or lack of response. This would be a risk as vaccinated individuals tend to let their guard down and become more lax in following COVID-19 safety measures.

Serological tests that measure the levels of antibodies could help to quantify the risk of an individual getting infected by COVID-19. This could then inform the countries’ effective vaccine distribution strategy. As vaccines are in low supply, countries could prioritise the vaccines to those with low levels of antibodies. Those who shown no response to the first vaccine could then be given another vaccine.

More studies needed to see what is adequate for such serology tests, and the levels of antibodies needed for the different variants of the vaccines. The world would benefit from WHO leadership for a united response – Dr Leong emphasised that the world will march out of this pandemic at the pace of the slowest nation. Coordination across countries to identify the best-performing vaccines and channeling resources to manufacture those in large scale; and coordination in the diagnostics industry to harmonise serology tests, will go a long way in the ongoing COVID-19 war.

Like this story? Subscribe for more

More Insights

September 23, 2021
Today’s hospitals are facing a tall order, balancing costs, high cleanliness requirements and also workplace safety. We look at how adoption of the right cleaning equipment can meet these requirements.
September 23, 2021
Thomson Hospital Kota Damansara shares about the various infection control measures it has taken, and how it ensures effective hospital cleaning standards
September 23, 2021
Cleaning carts are a common fixture in hospital wards and corridors, but usually go unnoticed. However, safe usage of appropriate carts is a key element in the overall infection control process